Category: Pharmaceuticals - Page 3
Rifampin drastically lowers levels of anticoagulants and antivirals by inducing liver enzymes, risking clotting or treatment failure. Learn how it affects warfarin, DOACs, and HIV drugs-and what to do instead.
Despite generics making up 90% of prescriptions, many doctors still doubt their effectiveness. This article explores why providers hesitate, what data they need, and how real-world evidence is slowly changing attitudes.
Antidepressants can trigger mania or rapid cycling in bipolar disorder. Learn why they're risky, which drugs are safer, what alternatives exist, and how to avoid dangerous treatment mistakes.
Family history and genetics play a major role in how your body responds to generic drugs. Learn how inherited gene variants affect drug metabolism, why some people have bad reactions, and what steps you can take to stay safe.
Many common medications can trigger dangerous heart rhythm problems. Learn the warning signs of drug-induced arrhythmias, which drugs are most risky, and how to manage them safely before it's too late.
Combining tricyclic antidepressants like amitriptyline with antihistamines such as Benadryl can cause dangerous anticholinergic overload, increasing risks of confusion, dementia, and delirium-especially in older adults. Safe alternatives exist.
Atazanavir remains a key HIV treatment option in 2025, especially for pregnant patients, those with prior resistance, and in low-resource settings. Learn how it works, its side effects, and why it's still used despite newer drugs.
Combining PDE5 inhibitors like Viagra or Cialis with nitrates can cause sudden, life-threatening drops in blood pressure. Learn why this interaction is dangerous, how long to wait between doses, and what alternatives exist.
Learn how to adjust antibiotic doses for kidney disease to avoid toxicity and treatment failure. Understand CrCl calculations, key drug adjustments, and why acute kidney injury changes everything.
Military deployment exposes medications to extreme heat, risking vaccine failure and drug degradation. Learn how temperature control, access delays, and climate change threaten soldier health-and what’s being done to fix it.
Proton pump inhibitors can severely reduce absorption of certain antifungals like itraconazole and ketoconazole, leading to treatment failure. Fluconazole is safer to combine with PPIs, but new research shows PPIs may also boost antifungal effectiveness in unexpected ways.
Mouth sores from medications like chemo and radiation are common but preventable. Learn evidence-based strategies to avoid them and manage pain effectively with proven treatments like cryotherapy, benzydamine, and Gelclair.