Tag: tricyclic antidepressants

Combining tricyclic antidepressants like amitriptyline with antihistamines such as Benadryl can cause dangerous anticholinergic overload, increasing risks of confusion, dementia, and delirium-especially in older adults. Safe alternatives exist.

A clear, side‑by‑side look at Amitriptyline (Elavil) and its top alternatives, covering uses, side effects, costs and how to pick the right drug for you.