macrophages In A Sentence

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• These macrophages are sometimes called 'heart failure cells ' because of their association with pulmonary congestion with congestive heart failure.
• The mediator molecules also alter the blood vessels to permit the migration of leukocytes, mainly neutrophils and macrophages, outside of the blood vessels ( extravasation ) into the tissue.
• Olive leaf has also been suggested to support innate immunity through their interactions with macrophages.
• In many ways, extravasated platelets in trauma perform a similar function to tissue macrophages and mast cells exposed to inflammatory process.
• HIV has other targets besides T cells, like the cells known as macrophages.
• Tingible body macrophages are present. No prominent nucleoli or irregular nuclear profiles are appreciated.
• CD11b has a vital role in activation of macrophages to destroy intracellularly ingested " T . whipplei " bacteria.
• They can occasionally appear in visceral organs. There is a central area of fibrinoid necrosis surrounded by pallisading epithelioid macrophages and other mononuclear cells.
• AIM: To study the activation and the immune regulation of paecilomyces cicadidae total polysaccharides on macrophages in old rats.
• Macrophages possess a repertoire of antimicrobial molecules packaged within their granules and lysosomes.
• An illustration through time - lapse film, light microscope slide and electron micrograph of the activities of macrophages.
• T helper cells, macrophages or dendritic cells ).
• Despite the destruction of platelets by splenic macrophages, the spleen is normally not enlarged.
• Macrophages and T lymphocytes demonstrated a marked expression of HLA-DR antigen.
• The center of the lesion consists of macrophages and epithelioid cells.
• An alternative means of diagnosis is by detecting pigment in macrophages of the lamina propria.
• In CT, they give rise to macrophages ( histiocytes ).
• Thromboxane A2 can also be produced in circulating monocytes and macrophages within atherosclerotic plaque (figure 1).
• Macrophages ( specifically histiocytes ) are the cells that define a granuloma.
• Rheumatic valvular lesions may also involve a cell-mediated immunity reaction as these lesions predominantly contain T-helper cells and macrophages.
• However, some " C . neoformans " cells can survive intracellularly in macrophages.
• David is well known for his expertise in using gene targeted macrophages to deliver cytokines to inflamed sites to provide in vivo biosensors.
• Brain macrophages ( microglia ) can regulate the number of neural precursor cells in the developing brain by phagocytosing these otherwise viable precursors and thus limiting neurogenesis.
• CLEC7A is expressed by macrophages, neutrophils and dendritic cells.
• The activated cells, called macrophages, were then injected.
• TLR7 recognizes single-stranded RNA in endosomes, which is a common feature of viral genomes which are internalised by macrophages and dendritic cells.
• During this process ICAM-4 binds to VLA-4, an erythroblast binding site, on adjacent erythroblasts and to ?v integrins on macrophages to help stabilise the erythroblastic islands.
• Infection of macrophages by FIPV is responsible for development of a fatal granulomatous vasculitis, or FIP ( see granuloma ).
• The myelocytic line ( granulocytes ) and to monocytes, macrophages, and dendritic cells of the innate immune system.
• Macrophages accumulate around the stent, and nearby smooth muscle cells proliferate.
• In the case of biological particles such as bacteria, this fluid opsonizes the particles to facilitate ingestion by macrophages.
• Result : GLB 7 increased the production of IP 3 and DAG in murine peritoneal macrophages.
• Lack of RIP140 leads to an inhibition of proinflammatory pathways in macrophages.
• In conclusion, the use of specific molecular probes and insitu hybridisation allows a functional analysis of tissue macrophages.
• Interleukin 12 ( IL - 12 ) is an important anti - tumor cytokine mainly secreted by monocytes, dendritic cells and macrophages.
• Histopathologic features of RA encompass infiltration by macrophages and T cells synovial lining hyperplasia, neoangiogenesis, pannus formation and destruction of cartilage and bone.
• Conclusion Apoptosis occurred in both infiltrating macrophages and intrinsic kidney cells and may play an important role in the progression of renal injury in the rat crescentic glomerulonephritis.
• The pale areas seen here are tophi, or aggregates of urate crystals surrounded by infiltrates of lymphocytes, macrophages, and foreign body giant cells.
• P2X receptors are expressed in cells from a wide variety of animal leukocytes, including lymphocytes and macrophages, and are present on blood platelets.
• But the virus lingers in disease-fighting T cells and macrophages.
• They are essential in B cell antibody class switching, in the activation and growth of cytotoxic T cells, and in maximizing bactericidal activity of phagocytes such as macrophages.
• However the recruited macrophages do not promote inflammatory response but rather regulate lipolysis.
• Tingible body macrophages ( TBMs ) -large phagocytic cells in the germinal centers of secondary lymph nodes -express CD68 protein.
• Macrophages can phagocytize and kill leptospira, while the pathogenic leptospira can evade the killing by macrophages.
• Thioglycolate broth is also used to recruit macrophages to the peritoneal cavity of mice when injected intraperitoneally.
• Identification of neutral cholesterol ester hydrolase, a key enzyme removing cholesterol from macrophages.
• Listeria monocytogenes live inside specific white blood cells called macrophages.
• In BLM group , PAI - 1 was expressed in macrophages and II type epithelial cell.
• Histopathological features are myocardial interstitium with abundant edema and inflammatory infiltrate, rich in lymphocytes and macrophages.
• This term refers to the vague resemblance of these macrophages to epithelial cells.
• Microscopically, Mycobacterium avium - intracellulare infection is marked by numerous acid fast organisms growing within macrophages.
• At high magnification, liquefactive necrosis of the brain demonstrates many macrophages at the right which are cleaning up the necrotic cellular debris.
• Gp120 binds to a CD4 and a co-receptor ( CCR5 or CXCR4 ), found on susceptible cells such as Helper T cells and macrophages.
• In particular, he is credited with the discovery of phagocytes ( macrophages ) in 1882.
• Methods The expression of T cells, B cells, macrophages, giant cells and granulocytes in temporal artery biopsy specimens from twenty patients with GCA was examined using immunohistochemistry.
• The demyelinating lesion presents T-cells and macrophages around blood vessels, with preservation of oligodendrocytes and signs of complement system activation.
• Macrophages and microglial cells are the cells infected by HIV in the central nervous system.
• Effect of Astragalus radix on proliferation and nitric oxide production of head kidney macrophages in Cyprinus carpio:an in vitro study .
• The organism's polysaccharide capsule makes it resistant to phagocytosis, and if there is no pre-existing anticapsular antibody, alveolar macrophages cannot adequately kill the pneumococci.
• Objective To study the role of zymosan in and the effects of total saponin of Panax notoginseng (PNS) on the formation of foam cells originating from peritoneal macrophages.
• Objective To study the changes of cyclooxygenase-2 (COX-2) in pulmonary intravascular macrophages stimulated by lipopolysaccharides .
• Evidence demonstrates that RhoGDI2 inhibits the endothelin axis and crosstalk with macrophages within the micrometastatic microenvironment to inhibit metastatic outgrowth.
• CCL2 is primarily secreted by monocytes, macrophages and dendritic cells.
• Macrophages in the pulp become activated after receiving two signals.
• The alarm marshals macrophages and other reinforcements to battle the invader.
• It is produced by certain tumor cell lines and by macrophages.
• The observation of edema in MR, and also the finding of inflation and macrophages in necropsied tissues, has led to successful administration of antiinflammatories.
• Alveolar macrophages ( dust cells ) engulf the red blood cells, and become engorged with brownish hemosiderin.
• Macrophages remove senescent erythrocytes, leukocytes, and megakaryocytes by phagocytosis and digestion.
• Infections of chickens with avian reovirus doesn' t disrupt the functional capabilities of their T-cells, but induces suppressor macrophages that inhibit T-cell function.
• The number and affinity coefficient of AGE receptors in peritoneal macrophages of rats supplemented with VC and VE for 5w were investigated using radiolabeled ligand binding experiments.
• Macrophages in the body protect against infection and gobble up debris.
• The iron release from macrophages is also reduced by ferroportin inhibition.
• In macrophages, it has also been shown to signal via STAT3.
• Nonetheless, false positives exist for maturing tissue macrophages and senescence-associated beta-galactosidase as well as for T-cells p16 Ink4A.
• Antigen-antibody complexes may be chemotactic for phagocytes, or they may activate complement, a process that produces both cell lysis and substances chemotactic for neutrophils and macrophages.
• Once the bacterium enters the host's monocytes, macrophages, or polymorphonuclear leukocytes, it becomes bloodborne ( septicemic ) and can grow.
• Conclusions Demyelinating pseudotumor is characterized by perivascular lymphocytes and diffusely distributed macrophages, while the lesion is usually observed with a texture of areosis change.
• They can leave the blood stream and are then referred to as tissue macrophages.
• Macrophages in Peyer's patches engulf " M . paratuberculosis " for the purpose of destroying the foreign invader, but for reasons yet unclear, these macrophages fail to do this.
• Pathogens engulfed by these macrophages are starved and easily inactivated.
• Within the brain, quinolinic acid is only produced by activated microglia and macrophages.
• Foreign materials are walled off by macrophages that may metamorphose into epithelioid cells, which are encircled by mononuclear leukocytes, forming granulomas.
• MIF may interact with the human immune system during the course of infection by altering the function of macrophages in the infected individual.
• RNA synthesis in macrophages, however, was improved as the dosage of actinomycin D increased.
• The pulmonary macrophages are the body's primary defence mechanism to contain M. tuberculosis.
• He first explored the application of statins in suppressing the inflammatory events in microglia, astroglia and macrophages.
• These negatively charged phospholipids are recognized by phagocytes such as macrophages.
• When added to autologous leishmania infected macrophages these T cells cause parasite death and secretion of large amounts of interferon-gamma and lymphotoxin.
• As with other types of giant cells, epithelioid macrophages fusing together causes these giant cells to form and grow.
• Macrophages exposed to dust have been shown to have markedly decreased chemotaxis.
• CD40 is constitutively expressed by antigen presenting cells, including dendritic cells, B cells and macrophages.
• "Cryptococcus neoformans " is an encapsulated yeast that can live in both plants and animals . " C . neoformans " usually infects the lungs, where it is phagocytosed by alveolar macrophages.
• The inactivation of macrophages allows for the dissemination of mycobacteria to other parts of the body.
• In tonsils and adenoids of HIV-infected patients, macrophages fuse into multinucleated giant cells that produce huge amounts of virus.
• V-ATPases are also found in the plasma membranes of a wide variety of cells such as intercalated cells of the kidney, osteoclasts ( bone resorbing cells ), macrophages, neutrophils, egg.
• It has been found that " Salmonella typhi " persists in infected mice macrophages that have cycled from an inflammatory state to a non-inflammatory state.
• The human body contains specialized cells called macrophages that remove worn-out cells by degrading them to simple molecules for recycling.
• Macrophages and other white blood cells concentrate by the tonsillar crypts as well, in response to the microorganisms attracted to the crypts.
• The macrophages, accompanied by Schwann cells, serve to clear the debris from the degeneration.