anergy In A Sentence
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- Objective:Study the correlation between T cell anergy and apoptosis.
- The enhanced cell surface expression of CTLA-4 is likely responsible for the induction of T cell anergy .
- At the cellular level, " anergy " is the inability of an immune cell to mount a complete response against its target.
- NFAT homodimers are directly responsible for the expression of anergy associated genes such as ubiquitin ligase T-cell, NFAT1, NFAT2 and NFAT4 and apparently are redundant to some extend.
- Introduction: Self tolerance is regarded as the anergy condition for the immune system to self antigens.
- These false negatives may occur because of higher rates of tuberculin anergy compared to other forms of tuberculosis.
- B-cell anergy can be induced by exposure to soluble circulating antigen, and is often marked by a downregulation of surface IgM expression and partial blockade of intracellular signaling pathways.
- Results IL 2 production was reduced significantly, but IL 10 production was increased gradually during the induction of T cell anergy.
- Aim To explore the molecular mechanism of T cell anergy induced by superantigen SEA.
- Howeer, some T cells are not actiated, in fact they are inactivated by a process called anergy or tolerance.
- This same positive and negative selection mechanism, but in peripheral tissues, is known as clonal anergy.
- Introduces the concepts of available anergy and reduced exergy by analysing the energy utilization process.
- Additional mechanisms of peripheral tolerance active in the periphery exist to silence these cells such as anergy, deletion, and regulatory T cells.
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